2020 – 2024 • Humboldt Postdoctoral Research Fellow • Research with DeBeer Research Group
2014 – 2020 • Ph.D. in Inorganic Chemistry • Research with Rose Research Group
Laboratory & Experimental Skills
Chemical Synthesis: Air-free synthesis, Schlenk techniques, ion separation, purification, & crystallization
Metalloproteins and biological materials
Work at synchrotron radiation sources: SSRL, CHESS, ESRF, Diamond, PETRA III, BESSY II
X-ray absorption spectroscopy (XAS, XANES, EXAFS)
X-ray emission spectroscopy (XES, HERFD-XAS, resonant XES)
EPR, NMR, IR, UV-vis spectroscopies; Mass Spectrometry
X-ray Diffraction (XRD)
X-ray Photoelectron Spectroscopy (XPS)
Laboratory Safety Officer; Chemical Ordering & Shipping; Glovebox Maintenance
Data Handling, Processing, and Visualization
Data processing in Python (Jupyter, Larch, VS Code, Spyder)
Data processing in MATLAB (EasySpin)
ChimeraX, PyMOL, CSD Conquest, ChemCraft, Demeter (Athena/Artemis)
Writing, Presentation, Figure Production, and General Office Skills
Web of Science, SciFinder, CSD Conquest
Proposal writing (beamtimes, fellowships)
Writing manuscripts (see Publications) and beamtime reports
Adobe Illustrator, Photoshop
Microsoft Office (Word, Excel, PowerPoint)
Google Docs, Sheets, Forms, Sites (Website Creation)
Languages
English (Native)
German (B1)
Max Planck Institute for Chemical Energy Conversion, Mülheim an der Ruhr, Germany
Postdoctoral Research Fellow, 2020–2024
Studied transition metal-centered small-molecule and biological catalytic systems by employing synchrotron-based hard X-ray spectroscopic techniques (XAS, XES, VtC data).
Led small teams through several synchrotron beamtime experiments at facilities including Diamond, SSRL, ESRF, and other sources.
Collaborated with and coordinated international teams across Europe to express and study LPMO structural and mechanistic attributes.
3 successful publications in high-quality scientific journals.
Awarded an Alexander von Humboldt Research Fellowship.
Presently contributing as a remote Guest Researcher.
The University of Texas at Austin, Austin, TX, U.S.A.
Graduate Research Associate, 2014–2020
Synthesis, separation/isolation, and characterization of charged and neutral inorganic iron-carbide and iron-sulfide clusters.
5 successful publications, including 4 primary works and 1 review/perspective
Performed duties as Laboratory Safety Officer. Helped to initialize a “Peer-2-Peer” safety check program with between research groups in the chemistry department.
Undergraduate Research Experiences
2011–2014
Austin College (Sherman, TX, U.S.A.): June 2011 – May 2014. Inorganic synthesis of Platinum complexes for use in Dye-Sensitized Solar Cell technology. 1 successful publication (first author paper as an undergraduate!)
University of Florida (Gainesville, FL, U.S.A.): Summer student, 2012. ESI Mass Spectrometry fragmentation pattern analysis
The University of Texas at Austin (Austin, TX, U.S.A.): Summer student, 2013. [Fe]-hydrogenase biomimetics. 1 publication (co-author).
The University of Texas at Austin, Austin, TX, U.S.A.
Teaching Assistant, 2014–2020
Courses taught:
General Chemistry Labs (Semesters 1 & 2)
Inorganic Chemistry Lab
Advanced Inorganic Chemistry Lab
Student Inquiry Across Disciplines (SIAD)
This is an interdisciplinary course which teaches incoming freshman how to do research. Students would design and execute their own research projects over the course of the semester.
Completed Teaching Certification in First-Year Interdisciplinary Instruction
Chemistry of Materials / Assembly of Matter (Lecture)
H2fromH2O, Chemistry and Sustainability Educational Outreach Program
Graduate volunteer
A program which shows modern chemistry research problems and strategies to middle- and high-school age students.
As a volunteer, I demonstrated water splitting experiments and the utilization of hydrogen fuels as a clean alternative energy to school students and the broader community.
Austin College Academic Skills Center, Sherman, TX, U.S.A.
Undergraduate Peer Tutor, 2012–2014
Tutoring undergraduate students in a breadth of subjects.
Subjects tutored: All chemistry, All math, Introductory physics, biology, and psychology.
Achieved CRLA Level III Master Tutor Certification.
Austin College Chemistry Department, Sherman, TX, U.S.A.
Undergraduate Teaching Assistant (Organic Chemistry Lab), 2012–2013
Teaching Certificate in First-Year Interdisciplinary Instruction • The University of Texas at Austin - School of Undergraduate Studies • Issued Jan 2018
CRLA Master Certified Tutor, Level III • Austin College Academic Skills Center • Issued May 2014
Description: "With this Research Fellowship the Alexander von Humboldt Foundation enables highly-qualified scientists and scholars from abroad who are just embarking on their academic careers and who completed their doctorates less than four years ago to spend extended periods of research in Germany."
Description: "This award is offered only to our best graduate students and is awarded for your excellent research and academic achievements."
Description: "This honor is awarded for your exemplary performance as a Teaching Assistant for the Department of Chemistry."
Description: "Because of your demonstrated excellence in inorganic chemistry at the undergraduate level.”
Description: "Established in spring 1995 by Mr. and Mrs. Joe Dennis and other alumni of the College in memory of Dr. Armendt, Austin College professor of chemistry from 1920 to 1937."
(Submitted) Dick, E.; Joseph, C.; Lynch, V. M.; Rose, M. J. Synthesis, Structure & Diphenylacetylene Reduction Reactivity of a Carbide-Supported Fe4Mo2 Carbonyl Cluster: A Higher Fe-Valence Hydride Intermediate for Enhanced Selectivity. Under review at Dalton Trans.
Joseph, C.; Tamhankar, A.; Golten, O.; Sengupta, K.; Jannuzzi, S. A. V.; Sørlie, M.; Kang, L.; Røhr, A. K.; Eijsink, V. G. H.; DeBeer, S. Structural and Electronic Modulations of LPMO upon Chitin Binding: Insights from X-ray Spectroscopy. Chem. Sci. 2025, 16 (48), 22952–22969. https://doi.org/10.1039/D5SC07620J
Issue Cover (Back): https://pubs.rsc.org/en/content/articlepdf/2025/sc/d5sc90279g
Munzone, A.; Pujol, M.; Tamhankar, A.; Joseph, C.; Mazurenko, I.; Réglier, M; Jannuzzi, S. A. V; Royant, A.; Sicoli, G.; DeBeer, S.; Orio, M.; Simaan, A. J.; Decroos, C. Integrated Experimental and Theoretical Investigation of Copper Active Site Properties of a Lytic Polysaccharide Monooxygenase from Serratia marcescens. Inorg. Chem. 2024, 63 (24), 11063. https://doi.org/10.1021/acs.inorgchem.4c00602
Hall, K. R.; Joseph, C.; Ayuso-Fernández, I.; Tamhankar, A.; Rieder, L.; Skaali, R.; Golten, O.; Neese, F.; Røhr, Å. K.; Jannuzzi, S. A. V.; DeBeer, S.; Eijsink, V. G. H.; Sørlie, M. A Conserved Second Sphere Residue Tunes Copper Site Reactivity in Lytic Polysaccharide Monooxygenases. J. Am. Chem. Soc. 2023, 145 (34), 18888. https://doi.org/10.1021/jacs.3c05342
Joseph, C.; Cobb, C. R.; Rose, M. J. Single-Step Insertion of Sulfides and Thiolate into Iron Carbide‐Carbonyl Clusters: Unlocking the Synthetic Door to FeMoco Analogues. Angew. Chem. Int. Ed. 2021, 60 (7), 3433. https://doi.org/10.1002/anie.202011517
Joseph, C.; Shupp, J. P.; Cobb, C. R.; Rose, M. J. Construction of Synthetic Models for Nitrogenase-Relevant NifB Biogenesis Intermediates and Iron-Carbide-Sulfide Clusters. Catalysts, 2020, 10 (11), 1317. https://doi.org/10.3390/catal10111317
Thesis: Joseph, C. Old Dog, New Tricks: Repurposing Iron-Carbide-Carbonyl Clusters as Precursors for Structural Modeling of the Nitrogenase Cofactor, The University of Texas at Austin, Austin, TX, 2020. http://dx.doi.org/10.26153/tsw/13865
McGale, J.; Cutsail III, G. E.; Joseph, C.; Rose, M. J.; DeBeer, S. Spectroscopic X‑ray and Mössbauer Characterization of M6 and M5 Iron(Molybdenum)-Carbonyl Carbide Clusters: High Carbide-Iron Covalency Enhances Local Iron Site Electron Density Despite Cluster Oxidation. Inorg. Chem. 2019, 58 (19), 12918–12932. https://doi.org/10.1021/acs.inorgchem.9b01870
Joseph, C.; Kuppuswamy, S.; Lynch, V. M.; Rose, M. J. Fe5Mo Cluster with Iron-Carbide and Molybdenum-Carbide Bonding Motifs: Structure and Selective Alkyne Reductions. Inorg. Chem. 2018, 57 (1), 20–23. https://doi.org/10.1021/acs.inorgchem.7b02615
Joseph, C.; Nesterov, V. N.; Smucker, B. W. Crystal structure of bis(acetonitrile-κN)(4,4′-di-tert-butyl-2,2′-bipyridine-κ2N,N′)platinum(II) bis(tetrafluoridoborate) packing as head-to-head dimers. Acta Crystallogr. Sect. E Crystallogr. Commun. 2018, 74 (5), 695–697. https://doi.org/10.1107/S2056989018005923
Kuppuswamy, S.; Wofford, J. D.; Joseph, C.; Xie, Z.; Ali, A. K.; Lynch, V. M.; Lindahl, P. A.; Rose, M. J. Structures, Interconversions, and Spectroscopy of Iron Carbonyl Clusters with an Interstitial Carbide: Localized Metal Center Reduction by Overall Cluster Oxidation. Inorg. Chem. 2017, 56 (10), 5998–6012. https://doi.org/10.1021/acs.inorgchem.7b00741
Muthiah, K. A. T.; Durgaprasad, G.; Xie, Z.-L.; Williams, O. M.; Joseph, C.; Lynch, V. M.; Rose, M. J. Mononuclear Iron(II) Dicarbonyls Derived from NNS Ligands – Structural Models Related to a “Pre‐Acyl” Active Site of Mono‐Iron (Hmd) Hydrogenase. Eur. J. Inorg. Chem. 2015, 2015 (10), 1675–1691. https://doi.org/10.1002/ejic.201403013
Joseph, C. LPMO “Gatekeeper” Substitution Evaluated by Cu K-edge X-ray Absorption and EPR Spectroscopies. International Symposium on relations between Homogeneous and Heterogeneous Catalysis (ISHHC19), 2022.
Thesis Seminar: Joseph, C. Old Dog, New Tricks: Repurposing Iron-Carbide-Carbonyl Clusters as Precursors for Structural Modeling of the Nitrogenase Cofactor. The University of Texas at Austin Department of Chemistry, 2020.
Joseph, C. Development of Preliminary Nitrogenase Mimics for Catalytic Nitrogen Fixation. ACS UT Student Chapter Seminar Series, 2016.
Joseph, C.; Tamhankar, A.; Golten, O.; Sengupta, K.; Sørlie, M.; Kang, L.; Jannuzzi, S. A. V.; Røhr, A. K.; Eijsink, V. G. H.; DeBeer, S. X-ray Spectroscopic Characterization of Chitin Binding by Lytic Polysaccharide Monooxygenase (LPMO). Gordon Research Conference: Metallocofactors, 2024.
Joseph, C.; Flöser, B.; Hall, K.; Sørlie, M.; Eijsink, V.; DeBeer, S. Effects of LPMO “Gatekeeper” Substitution at the Cu Site: Evaluation by Cu K-edge X-ray Absorption and EPR Spectroscopy. Gordon Research Conference: Metallocofactors, 2022.
Joseph, C.; Kuppuswamy, S.; Rose, M. J. Synthetic iron-molybdenum/interstitial carbide clusters as structural models of the FeMoco carbide. Gordon Research Conference: Metallocofactors, 2018.
Joseph, C.; Kuppuswamy, S.; Rose, M. J. Isolation of a synthetic nitrogenase-relevant iron-molybdenum/interstitial-carbide cluster. 254th ACS National Meeting & Exposition, 2017, INOR-154.
Joseph, C.; Muthiah, K. A. T.; Durgaprasad, G.; Rose, M. J. Biomimetic Modeling of [Fe]-Hydrogenase: Ligation of N,N,S Schiff Base Ligands in FeII Complexes. UT Austin IMPACT summer program (REU), 2013.
Joseph, C.; Smucker, B. W. Making a versatile corner for a light-harvesting supramolecular square using platinum(II) and diamine. 67th Southwest Regional Meeting of the American Chemical Society, 2011, SWRM-414.
MPI CEC LinkedIn post: https://www.linkedin.com/posts/max-planck-institute-for-chemical-energy-conversion_backcover-spectroscopy-openaccess-activity-7416444914839822337-3TV7
Enzyme Dynamics Unlocked: LPMO’s Dance with Chitin Revealed: https://www.cec.mpg.de/en/detail-view/enzymdynamik-entschluesselt-der-tanz-von-lpmo-mit-chitin-enthuellt
Enzymdynamik entschlüsselt: Der Tanz von LPMO mit Chitin enthüllt: https://www.cec.mpg.de/de/news-events/detailansicht/enzymdynamik-entschluesselt-der-tanz-von-lpmo-mit-chitin-enthuellt
Chris Joseph receives Humboldt Research Fellowship: https://www.cec.mpg.de/en/detail-view/chris-joseph-erhaelt-humboldt-forschungsstipendium
Chris Joseph erhält Humboldt-Forschungsstipendium: https://www.cec.mpg.de/de/news-events/detailansicht/chris-joseph-erhaelt-humboldt-forschungsstipendium
Chemistry Graduate Student Awards Showcase: https://chemistry.utexas.edu/news/announcements/chemistry-graduate-student-awards-showcase